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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Flexner–Wintersteiner rosette ： ウィキペディア英語版 Flexner–Wintersteiner rosette Flexner–Wintersteiner rosette is a spoke and wheel shaped cell formation seen in retinoblastoma and certain other ophthalmic tumors.〔(Definition of 'rosette' ), from The Free Dictionary. Retrieved 6 January 2010.〕 A ''rosette'' is a structure or formation resembling a rose, such as the clusters of polymorphonuclear leukocytes around a globule of lipid nuclear material, as observed in the test for disseminated lupus erythematosus.〔 ==History== Flexner–Wintersteiner rosettes were first described by Simon Flexner (1863–1946), a physician, scientist, administrator, and professor of experimental pathology at the University of Pennsylvania (1899–1903). Flexner noted characteristic clusters of cells in an infantile eye tumor which he called retinoepithelioma.〔Flexner S. A peculiar glioma (neuroepithelioma?) of the retina. Johns Hopkins Hosp Bull 1891;2:115–19〕〔Schatski SC. Simon Flexner. AJR Am J Roentgenol 1997;169:1395–96.〕〔Bendiner E. Simon Flexner: his "rock" was for the ages. Hosp Pract 1988;23:213–66〕 A few years later, in 1897, Austrian ophthalmologist Hugo Wintersteiner (1865–1946) confirmed Flexner’s observations and noted that the cell clusters resembled rods and cones.〔Wintersteiner H. Die zellen der geschwulst. In: Das neuroepithelioma retinae: Eine anatomische und klinishe studie. Leipzig: Franz Deuticke; 1897:12–16〕 These characteristic rosette formations were subsequently recognized as important features of retinoblastomas. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Flexner–Wintersteiner rosette」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.